Applicable properties of cucurbiturils

Galit Parvari, Ofer Reany, Ehud Keinan

פרסום מחקרי: פרסום בכתב עתסקירהביקורת עמיתים


This account highlights three significant fields of applications for cucurbiturils (CBs). The first relates to cucurbituril-based devices and sensors involving spectral effects associated with the formation and dissociation of inclusion complexes. The second refers to the use of CBs as catalysts that control the rate and selectivity of chemical reactions. The third deals with the potential use of CBs for the assembly of mechanical devices and molecular motors. An example of the sensor application is based on the discovery that 4-aminobipyridine derivatives form strong inclusion complexes with CB6, exhibiting remarkably large enhancements of fluorescence intensity and quantum yields. This reversible binding phenomenon can be used for the design of switchable beacons that can be incorporated into cascades of binding networks for various applications. The second application is exemplified by selective, enhanced photoaddition reactions as well as [3+2]cycloaddition and other reactions mediated by the CB cavity. The third application is based on the idea that low-barrier molecular rotary motors having rotaxane architecture can be constructed using a cucurbituril host and a polyyne guest serving as stator and rotator, respectively. The "low friction" between these components is supported by molecular mechanics calculations with model systems and experimentally verified by X-ray crystallography with several synthetic host-guest complexes, all suggesting that the diyne rod floats at the center of the macrocyclic host with no apparent van der Waals contacts between them.

שפה מקוריתאנגלית
עמודים (מ-עד)646-663
מספר עמודים18
כתב עתIsrael Journal of Chemistry
מספר גיליון5-6
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - מאי 2011
פורסם באופן חיצוניכן

טביעת אצבע

להלן מוצגים תחומי המחקר של הפרסום 'Applicable properties of cucurbiturils'. יחד הם יוצרים טביעת אצבע ייחודית.

פורמט ציטוט ביבליוגרפי