Acetylcholine receptor and myogenic factor gene expression in Torpedo embryonic development

Orna Asher, Sara Fuchs, Miriam C. Souroujon

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים


The mRNA levels of acetylcholine receptor (AChR) and myogenic factors were followed during embryonic development of Torpedo skeletal muscle and its homologue, the electric organ. A different developmental pattern of AChR gene expression was found in these two tissues: a slight decrease in the muscle, and a marked increase, concomitant with synapse formation, in the electric organ. However, the developmental pattern of MyoD and MRF4 mRNA levels was similar in both tissues, with no significant changes during development. This is in contrast with the sharp increase in the expression of AChR in the electric organ and may suggest that the burst in the expression of AChR during the differentiation of myotubes into electrocytes is not regulated by changes in the myogenic factor mRNA levels.

שפה מקוריתאנגלית
עמודים (מ-עד)1581-1584
מספר עמודים4
כתב עתNeuroReport
מספר גיליון13
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - אוג׳ 1994

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