A non-symmetrical p97 conformation initiates a multistep recruitment of Ufd1/Npl4

Keyphrases

• ATPase Cycle 20%
• Cryo-EM Structure 20%
• Further Analysis 20%
• In Vitro Experiment 20%
• Non-axisymmetric 100%
• NPL4 20%
• Nucleotide State 20%
• Protomers 20%
• Structural Phase Transition 40%
• Substrate Processing 40%
• Ufd1-Npl4 100%

Biochemistry, Genetics and Molecular Biology

• Adenosine Diphosphate 50%
• Adenosine Triphosphate 75%
• ATPase 25%
• Conformation 100%
• Cryo-Electron Microscopy 25%
• P97 100%
• Protomer 25%