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Stalled proteasomes are directly relieved by P97 recruitment
Elada Isakov,
Ariel Stanhill
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Keyphrases
Adaptor
100%
Cell Regulation
100%
Cellular Proteins
100%
Deubiquitination
100%
Enhanced Activity
100%
Functional Complexity
100%
Hexameric ATPase
100%
NPL4
100%
Protease
100%
Proteasome Activity
100%
Protein Degradation
100%
Protein Misfolding
100%
Proteolysis
100%
S Gate
100%
Selective Binding
100%
Substrate Delivery
100%
Ufd1
100%
UPS Impairment
100%
Biochemistry, Genetics and Molecular Biology
ATPase
12%
Cofactor
12%
Deubiquitination
12%
Endoplasmic-Reticulum-Associated Protein Degradation
12%
P97
100%
Protease
12%
Proteasome
100%
Protein Catabolism
25%
Protein Misfolding
12%