Insertion of an NPVY sequence into the cytosolic domain of the erythropoietin receptor selectively affects erythropoietin-mediated signalling and function

Keyphrases

• Cytoplasmic Domain 100%
• Erythropoietin Receptor 100%
• Erythropoietin 100%
• Cell Surface 16%
• Surface Level 11%
• Surface Expression 11%
• Phosphorylation 5%
• Cell Proliferation 5%
• Downstream Signaling 5%
• Intracellular Level 5%
• Apoptosis 5%
• Induced Apoptosis 5%
• Extracellular Signal-regulated Kinase 1/2 5%
• Janus Kinase 2 (JAK2) 5%
• Erythropoiesis 5%
• Signal Transducer and Activator of Transcription 5 5%
• Secondary Anemia 5%
• Low Expression 5%
• Cell Protection 5%
• Erythropoietin Levels 5%
• Selective Effect 5%
• Cell Surface Receptor 5%
• Erythroid Progenitors 5%
• Etoposide 5%
• Intracellular Domain 5%

Biochemistry, Genetics and Molecular Biology

• Erythropoietin Receptor 100%
• Erythropoietin 100%
• Surface Property 26%
• Wild Type 5%
• Cell Proliferation 5%
• Eicosanoid Receptor 5%
• Extracellular Signal-Regulated Kinases 5%
• Maturation 5%
• Erythropoiesis 5%
• STAT5 5%
• Progenitor Cell 5%
• Cell Surface Receptor 5%
• Janus Kinase 2 5%
• Cell Protection 5%

Immunology and Microbiology

• Erythropoietin Receptor 100%
• Erythropoietin 100%
• Cell Surface 33%
• Wild Type 5%
• Cell Proliferation 5%
• Maturation 5%
• STAT5 5%
• Erythropoiesis 5%
• Cell Protection 5%