The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast

Keyphrases

• Mammalian Target of Rapamycin (mTOR) 100%
• Fission Yeast 100%
• Aspartate Aminotransferase 100%
• Aspartate 38%
• Glutamine 30%
• Rapamycin 15%
• Schizosaccharomyces Pombe 15%
• Arginine 15%
• Asparagine 15%
• Evolutionarily Conserved 7%
• Cell Growth 7%
• Amino Acids 7%
• Fission Yeast Schizosaccharomyces Pombe 7%
• Cell Proliferation 7%
• Nitrogen Starvation 7%
• Vegetative Growth 7%
• Gain-of-function mutation 7%
• Catalytic Site 7%
• Catalytic Activity 7%
• Key Metabolic Enzymes 7%
• MTOR Inhibitor 7%
• Mimic Loss 7%
• Glutamine Synthetase Inhibitor 7%
• Genetic Screening 7%
• Methionine 7%
• Auxotrophy 7%
• Site Substitution 7%
• Methionine Sulfoximine 7%
• Nutritional Signals 7%

Biochemistry, Genetics and Molecular Biology

• Fission Yeast 100%
• Mammalian Target of Rapamycin Complex 1 100%
• Aspartate Transaminase 100%
• Glutamine 30%
• Arginine 15%
• Serine 15%
• Asparagine 15%
• Cell Growth 7%
• Amino Acids 7%
• Auxotrophy 7%
• Schizosaccharomyces Pombe 7%
• Enzyme 7%
• Cell Proliferation 7%
• Loss of Function Mutation 7%
• Genetic Screen 7%
• Glutamine Synthetase 7%
• Methionine 7%
• Vegetative Growth 7%

Immunology and Microbiology

• Fission Yeast 100%
• Mammalian Target of Rapamycin Complex 1 100%
• Sirolimus 15%
• Cell Growth 7%
• Auxotrophy 7%
• Schizosaccharomyces Pombe 7%
• Vegetative Growth 7%
• Cell Proliferation 7%
• Loss of Function Mutation 7%