ملخص
Dead Sea climatotherapy (DSC) is a therapeutic modality for a variety of chronic skin conditions, yet there has been scarce research on the relationship between the cutaneous microbiota and disease states in response to DSC. We characterized the skin bacterial and fungal microbiome of healthy volunteers who underwent DSC. Bacterial community diversity remained similar before and after treatment, while fungal diversity was significantly reduced as a result of the treatment. Individuals showed greater inter-individual than temporal bacterial community variance, yet the opposite was true for fungal community composition. We further identified Malassezia as the genus driving temporal mycobiome variations. The results indicate that the microbiome remains stable throughout DSC, while the mycobiome undergoes dramatic community changes. The results of this study will serve as an important baseline for future investigations of microbiome and mycobiome temporal phenomena in diseased states.
اللغة الأصلية | الإنجليزيّة |
---|---|
الصفحات (من إلى) | 256-261 |
عدد الصفحات | 6 |
دورية | Acta Dermato-Venereologica |
مستوى الصوت | 98 |
رقم الإصدار | 2 |
المعرِّفات الرقمية للأشياء | |
حالة النشر | نُشِر - فبراير 2018 |
ملاحظة ببليوغرافية
Publisher Copyright:© 2018 Acta Dermato-Venereologica.