Combining 16S rRNA gene variable regions enables high-resolution microbial community profiling

Keyphrases

• 16S rRNA Gene 100%
• 16S rRNA Gene Sequencing 20%
• Amplicon 40%
• Amplicon Length 20%
• Bacterial Biomass 20%
• Bacterial Isolates 20%
• Biological Samples 20%
• Computational Framework 20%
• Convex Optimization Problem 20%
• Core Genome multilocus Sequence Typing (cgMLST) 20%
• De-facto 20%
• Downstream Analysis 20%
• Drosophila Melanogaster 20%
• Fast Reconstruction 20%
• Fold Increase 20%
• Formalin-fixed 20%
• Fragmented DNA 40%
• Full-length 16S rRNA Gene 20%
• Gene-based 20%
• Harsh Conditions 20%
• High-resolution 100%
• High-resolution Profiling 20%
• Human Gut 20%
• Human Microbiome Project 20%
• In Silico Modeling 20%
• Large Coverage 20%
• Low Biomass 20%
• Microbial Community 20%
• Microbial Community Profiling 100%
• Microbial Diversity 20%
• Microbiome 20%
• Multiple Regions 60%
• Next-generation Sequencing Methods 20%
• Paraffin-embedded Samples 20%
• Primer Pairs 40%
• Read Length 60%
• Sampling numbers 20%
• Sequence Method 20%
• Sequencing Depth 20%
• Sequencing Platforms 20%
• Short Reads 20%
• Shotgun Sequencing 20%
• Specimen Preparation 20%
• Ultra-long Reads 20%

Immunology and Microbiology

• Amplicon 60%
• Drosophila Melanogaster 20%
• Framework Region 60%
• Gene Sequence 20%
• Human Microbiome Project 20%
• Microbial Diversity 20%
• Microbiome 20%
• Multilocus Sequence Typing 20%
• Next Generation Sequencing 20%
• RNA Gene 100%

Biochemistry, Genetics and Molecular Biology

• 16S Ribosomal RNA 100%
• Amplicon 50%
• Drosophila Melanogaster 16%
• Framework Region 50%
• Gene Sequence 16%
• Human Microbiome Project 16%
• Microbial Diversity 16%
• Microbiome 16%
• Multilocus Sequence Typing 16%
• Next Generation Sequencing 16%
• Reconstruction 16%
• Shotgun Sequencing 16%